We have successfully developed a software program for monitoring/analyzing these Drug-Drug & Drug-Herb Interactions. And we are on course to incorporate the MedChecker® into EMDEX 2018.
See the sample Amiodarone Interaction monograph below.
|AMIODARONE / AZITHROMYCIN Interaction Monograph|
|Mechanism||Azithromycin may enhance the QTc-prolonging effect of Amiodarone.|
|Effects||Co-administration of Amiodarone and Azithromycin may result in additive QTc prolongation or other serious cardiac events e.g., torsades de pointes (TdP), cardiac arrest. The risk is further worsened in patients with cardiac disease, electrolyte imbalance, elderly, etc.|
|Recommendations||The use of Azithromycin with Class III antiarrhythmic agents generally should be avoided. Most health facilities may not have adequate facilities to monitor the cardiac function closely|